At an oral dose of 2000 mg/kg/working day in rats, maternal toxicity and deaths ended up witnessed with an increased incidence of early fetal resorption; spontaneous abortions happened in cynomolgus monkeys with the maternally toxic oral dose of 2000 mg/kg/day; there isn't any enough and properly-controlled trials in pregnant women; https://steveno776zku9.wikievia.com/user