Arteries are thick-walled vessels intended to tackle higher strain since they carry oxygenated blood from the center. They have 3 layers: Tunica intima: The innermost layer manufactured from endothelial cells. Peripheral artery disease: A blockage with your legs. Complete loss of circulation can cause gangrene and loss of a limb. https://www.sgvascularctr.com/an-introduction-to-vascular-surgery-in-singapore/